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Combining hypofractionated radiation therapy with immunotherapy for anorectal malignant melanoma: a case report

  
@article{TRO4816,
	author = {Wei-Jun Wang and Kuan-Der Lee and Wei-Yu Chen and Jeng-Fong Chiou and Long-Sheng Lu},
	title = {Combining hypofractionated radiation therapy with immunotherapy for anorectal malignant melanoma: a case report},
	journal = {Therapeutic Radiology and Oncology},
	volume = {3},
	number = {0},
	year = {2019},
	keywords = {},
	abstract = {A 69-year-old man was diagnosed stage II anorectal malignant melanoma. He received radiotherapy which consisted of 25 Gy in 5 fractions to primary lesions and whole pelvis. He started pembrolizumab 3 weeks after the completion of radiotherapy. The treatment was complicated by CTCAE v4.0 grade 3 diarrhea. Ten weeks after radiotherapy, near total regression of the primary lesion as well as lymph nodes were found. The patient continued triweekly pembrolizumab and local recurrence was noted at 9 months after the initial diagnosis. Treating anorectal malignant melanoma with radiation assisted immunotherapy is worth considering and further study is warranted.},
	issn = {2616-2768},	url = {https://tro.amegroups.org/article/view/4816}
}