Article Abstract

Teachings of our translational studies on boron neutron capture therapy (BNCT): thinking “outside the box”

Authors: Amanda E. Schwint, Marcela A. Garabalino, Andrea Monti Hughes, Emiliano C. C. Pozzi, Elisa M. Heber, Mónica A. Palmieri, Verónica A. Trivillin

Abstract

BNCT is a technique for the treatment of solid tumors. BNCT is considered a binary technique because it involves two components that exert little or no action individually but induce a significant effect when they combine. BNCT is based on the combination of neutron irradiation and the administration of 10B compounds that are incorporated selectively by tumor tissue via different mechanisms, depending on the boron carrier.